Formulation and Evaluation of Transdermal Patch of Diclofenac Sodium
نویسندگان
چکیده
منابع مشابه
A comparative evaluation of diclofenac sodium transdermal patch, oral diclofenac sodium with intramuscular injections of diclofenac sodium in patients suffering from oral pain: A randomized control trial
Background Newer drug delivery systems such as transdermal patches using pain relieving or modifying agents emerged as a mainstream treatment protocol for management of pain on the outpatient basis. The administration of diclofenac 100 mg in the transdermal patch in the patients having dental pain due to periapical/periodontal infections was evaluated. Materials and Methods Ninety patients of...
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The purpose of this research was to develop a matrix-type transdermal therapeutic system containing drug heparin sodium with different ratios of hydrophilic polymeric systems by the solvent evaporation technique by using 30% (w/w) of PEG 400 LR to the dry polymer weight, incorporated as plasticizer. Different concentrations of oleic acid and isopropyl myristate were used to enhance the transder...
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Repaglinide has the half life of 1 hour, and bioavailability in the body is 56% due to first-pass metabolism. The total daily dose of Repaglinide is 16 mg (e.g., 4 mg four times daily depending on meal patterns); hence, it required frequent dosing. Transdermal patch of Repaglinide was prepared to sustain the release and improve bioavailability of drug and patient compliance. Different formulati...
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Bilayerd films were prepared by solvent casting technique using different concentration of two polymers namely, sodium alginate and pectin. The backing membrane was prepared by using sodium alginate. The drug containing layer was prepared by using pectin. Different concentrations of plasticizers and permeation enhancers were added. Prepared films were evaluated for surface properties, weight va...
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The aim of the present study was to prepare and evaluate different formulations of Diclofenac diethylammonium in microemulsion base with a view to enhance its permeability through the skin. Various o/w and w/o microemulsions of Diclofenac diethylammonium were prepared by the spontaneous emulsification methods. Isopropyl myristate was used as oil phase, Polyoxyethylenesorbitan monooleate and Sor...
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ژورنال
عنوان ژورنال: Global Journal of Pharmacy & Pharmaceutical Sciences
سال: 2018
ISSN: 2573-2250
DOI: 10.19080/gjpps.2018.04.555647